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Liver Function Tests (LFTs) are a group of blood tests used to assess liver health and function. They measure enzymes and substances such as ALT, AST, ALP, bilirubin, and albumin. Abnormal levels may indicate liver damage or conditions like hepatitis, cirrhosis, or fatty liver disease. LFTs are important for diagnosis, monitoring liver health, and evaluating treatment effectiveness.
Serum Bilirubin (Total)
Serum Bilirubin (Direct)
Serum Bilirubin (Indirect)
SGPT (ALT)
SGOT (AST)
Serum Alkaline Phosphatase
Serum Protein
Serum Albumin
Globulin
A/G Ratio
A Liver Function Test (LFT) is a group of blood tests used to evaluate the health and performance of the liver. It measures levels of key enzymes, proteins, and substances such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin, and albumin. These components help indicate how well the liver is functioning and whether there is any damage or inflammation
LFTs are commonly used to diagnose liver conditions such as hepatitis, fatty liver disease, and cirrhosis. They also help monitor existing liver disorders and assess the effectiveness of treatments. Regular testing is important for early detection, especially in individuals with risk factors like alcohol use, medications, or chronic diseases.
Here’s what an ideal Liver Function Test (LFT) report format should include:
All LFT parameters should be presented in a well-structured tabular format with columns such as Test Name, Result, Unit, and Reference Range. Key parameters include:
Values falling outside the normal range should be clearly highlighted (e.g., bold, color-coded, or flagged as High/Low) to improve readability and quick clinical interpretation.
Each parameter must include appropriate reference ranges. Some values may vary based on age, gender, and laboratory standards, so accurate reference intervals are essential for proper interpretation.
A brief interpretation section helps both clinicians and patients understand the results. For example:
Modern lab software often auto-generates these interpretations, making reports more patient-friendly and reducing manual effort.
In Curofyx software, this is the inbuilt interpretation for Complete Blood Count (CBC)
Liver Function Blood Test gives an insight into your liver health and helps identify problems like hepatitis, cirrhosis, and fatty liver disease, which may cause similar symptoms but require different treatments to recover.
Besides diagnosing liver problems, LFT’s also monitor overall liver functioning. Monitoring helps people with liver disease or taking medication, as it helps screen whether the treatment works fine or requires adjustments. Moreover, Liver Function Tests help determine if someone is at risk of developing liver diseases. Apart from assessing your chances, this test also checks the severity of the liver damage to help the doctor plan and prescribe appropriate treatment.
Increased in: Acute or chronic hepatitis, cirrhosis, biliary tract obstruction, toxic hepatitis, neonatal jaundice (neonatal hyperbilirubinemia), congenital liver enzyme abnormalities (Dubin-Johnson, Rotor, Gilbert, Crigler-Najjar syndromes), fasting, hemolytic disorders. Hepatotoxic drugs.
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